Diethylhexyl Butamido Triazone is a highly photostable, oil-soluble organic UV filter that provides potent protection against UVB and UVA II radiation. Often recognized by the trade name Iscotrizinol, it is esteemed in high-SPF formulations for its ability to maintain efficacy under prolonged sun exposure at remarkably low concentrations.
- INCI Name:
- Diethylhexyl Butamido Triazone
- Chemical/Scientific Name:
- Bis(2-ethylhexyl) 4,4′-[[6-[[4-[[(1,1-dimethylethyl)amino]carbonyl]phenyl]amino]-1,3,5-triazine-2,4-diyl]diamino]bisbenzoate
- Common Aliases:
- Iscotrizinol, Uvasorb HEB, DBT
| Category: | Sun Protection |
| Source Origin: | Synthetic |
| Comedogenic Rating: | 0 (N/A as a pure powder; dependent on carrier oil) |
| Primary Industries: | Cosmetics, Personal Care, Sunscreen manufacturing |
| Solubility: | Oil-soluble (Lipophilic) |
At a Glance: Properties & Effects
| Sun Protection: | |
| Formula Stability: | |
| Texture Enhancement: | |
| Irritation Risk: |
- Primary Benefits: Exceptional photostability, high UVB absorption efficiency, and water-resistance support due to lipophilic nature.
- Potential Risks: Limited UVA I coverage, potential for staining clothing, and regulatory restrictions in specific regions like the United States.
Biological Action & Cosmetic Profile
This triazine-derivative functions as a chemical (organic) sunscreen agent by absorbing ultraviolet radiation and converting it into harmless thermal energy. Its molecular structure is specifically tuned to peak at approximately 310 nm, placing its maximum efficacy squarely within the UVB range. Unlike older filters that degrade rapidly, Diethylhexyl Butamido Triazone retains roughly 90% of its filtering capacity even after 25 hours of continuous UV exposure. This inherent stability ensures that the SPF value stated on a product remains consistent throughout the duration of wear.
The large molecular weight of Diethylhexyl Butamido Triazone prevents it from penetrating the stratum corneum. From a toxicological perspective, this lack of dermal absorption minimizes the risk of systemic exposure or endocrine disruption, a common concern with smaller UV filters like Benzophenone 3. Because the molecule is highly hydrophobic, it integrates seamlessly into the lipid phase of an emulsion, often dissolved in emollients like C12 15 Alkyl Benzoate or Caprylic Capric Triglyceride. This characteristic also contributes to the water-resistance of the final cosmetic product, as it does not easily wash away when the user perspires or swims.
Efficiency distinguishes this filter from many of its peers. Formulators can achieve a high Sun Protection Factor (SPF) using lower concentrations compared to traditional filters such as Octocrylene. While it is structurally similar to Ethylhexyl Triazone, the “butamido” group in its chemical architecture enhances its oil solubility, making it easier to incorporate into lightweight, non-greasy formulations that appeal to consumers seeking high-performance sun care without a heavy skin feel.
Broader Applications & Origins
Originally developed in Europe to meet the demand for photostable UV filters, this ingredient has become a staple in high-end sunscreens across the EU, Asia, and Australia. Its synthesis involves advanced triazine chemistry, resulting in a fine, yellowish powder that requires specific ester solvents for complete dissolution. Beyond standard sunscreens, it is frequently utilized in daily moisturizers, hair care products designed for UV protection, and color cosmetics to prevent photo-induced degradation of the product itself.
Routine Integration
- Synergies: Pairs exceptionally well with Butyl Methoxydibenzoylmethane (Avobenzone) to stabilize the latter and extend UVA protection. It also works in tandem with Titanium Dioxide or Zinc Oxide to create broad-spectrum coverage. The addition of antioxidants like Tocopherol can further neutralize free radicals generated by the sun.
- Conflicts: There are no known major skincare ingredient conflicts. However, it requires an oil-based environment or specific solvents to remain stable in a formula; thus, it is rarely found in purely water-based, oil-free serums.
Clinical Consensus & Safety
The Scientific Committee on Consumer Safety (SCCS) and various international regulatory bodies have rigorously evaluated Diethylhexyl Butamido Triazone. It is currently approved for use in the European Union at a maximum concentration of 10%. Clinical studies indicate a very low potential for skin sensitization or photoallergy. While it is not yet monographed by the FDA for use in the United States, its long-standing safety record in other strictly regulated markets like Japan and Australia supports its profile as one of the safest and most reliable modern UV filters available today.
Is Diethylhexyl Butamido Triazone safe for sensitive skin?
Yes, its large molecular size prevents skin penetration, significantly reducing the likelihood of irritation or allergic reactions. It is generally considered safer for sensitive skin than older, more reactive chemical filters.
Does this ingredient provide full UVA protection?
It provides excellent protection in the UVA II range (320-340 nm) but lacks significant coverage in the UVA I range (340-400 nm). For full-spectrum protection, it must be combined with filters that specifically target long-wave UVA.
Why is this ingredient not in US-based sunscreens?
The FDA classifies sunscreens as over-the-counter (OTC) drugs rather than cosmetics. Because the FDA has not updated its list of approved UV filters (the Sunscreen Monograph) in decades, many modern, highly effective filters used globally remain unavailable in products manufactured in the US.