PEG-75 Lanolin is a water-soluble emollient and surfactant derived from sheep’s wool wax that restores essential lipids to the skin barrier. It functions as an effective skin conditioner and emulsion stabilizer, providing the moisturizing benefits of lanolin without the heavy, occlusive feel of the raw material.
- INCI Name:
- PEG-75 Lanolin
- Chemical/Scientific Name:
- Polyethylene glycol (75) lanolin
- Common Aliases:
- Ethoxylated Lanolin, Polyoxyethylene (75) Lanolin
| Category: | Softeners |
| Source Origin: | Animal-derived (Sheep’s wool) |
| Comedogenic Rating: | 0–1 |
| Primary Industries: | Cosmetics, Dermatology, Hair Care |
| Solubility: | Water-soluble |
At a Glance: Properties & Effects
| Hydration/Moisture | |
| Barrier Repair | |
| Texture Enhancement | |
| Irritation Risk |
- Primary Benefits: Lipid replenishment, skin softening, emulsion stabilization, and improved wash-off in cleansers.
- Potential Risks: Minimal; rare wool wax allergy sensitivity in specific populations.
Biological Action & Cosmetic Profile
Chemical modification through ethoxylation transforms hydrophobic lanolin into this versatile, water-soluble material. By reacting raw lanolin with 75 units of ethylene oxide, formulators create a molecule that integrates seamlessly into Aqua-based systems. This process maintains the lipid-replenishing profile of the original wax while significantly reducing its characteristic stickiness and odor.Skin physiology benefits from the complex mixture of esters, diesters, and hydroxy esters found in this derivative. These lipids closely mimic the composition of human sebum and the stratum corneum’s intercellular matrix, which contains Cholesterol and free fatty acids. When applied, the ingredient forms a non-occlusive, breathable film that prevents transepidermal water loss (TEWL) and facilitates the repair of a compromised skin barrier.The surfactant properties of this ethoxylated wax also serve a structural role in cosmetic chemistry. It acts as a secondary emulsifier and superfatting agent in surfactant-based products like body washes and shampoos. By depositing a thin protective layer on the skin during the rinsing process, it mitigates the drying effects often associated with harsh detergents.
Broader Applications & Origins
While raw lanolin has been used for centuries as a potent balm, PEG-75 Lanolin is a modern staple in sophisticated topical formulations. Its origin remains the wool of sheep, where the wax naturally protects the animal’s fleece from environmental stressors. Unlike Petrolatum or Mineral Oil, this ingredient is bio-based and renewable. It is frequently selected for medical-grade topical ointments, baby care products, and “leave-on” moisturizing lotions due to its high degree of purity and compatibility with human skin.
Routine Integration
- Synergies: Works exceptionally well with humectants like Glycerin to lock in moisture and combines effectively with fatty alcohols like Cetyl Alcohol to create stable, creamy textures.
- Conflicts: No known significant ingredient conflicts; universally compatible with most active substances.
Clinical Consensus & Safety
The Cosmetic Ingredient Review (CIR) Expert Panel has evaluated the safety of lanolin-derived polyethylene glycol ethers multiple times, concluding they are safe for use in cosmetics. Dermatological studies indicate that the incidence of sensitivity to PEG-75 Lanolin is extremely low, even among individuals with known “wool allergies,” as the ethoxylation and purification processes remove most potential protein impurities. It is non-sensitizing and non-irritating at standard formulation concentrations, typically ranging from 0.5% to 5.0%.
Is PEG-75 Lanolin vegan?
No, it is not vegan. It is derived from wool wax obtained from sheep. However, it is considered cruelty-free as the wool is harvested during the standard shearing process without harming the animal.
Will this ingredient clog my pores?
It is very unlikely to cause breakouts. While raw lanolin has a moderate comedogenic profile, the PEG-75 version is ethoxylated and water-soluble, which significantly reduces its ability to clog pores compared to the parent wax.
How does it differ from regular lanolin?
The primary difference is solubility and texture. Regular lanolin is a thick, greasy, water-insoluble wax. PEG-75 Lanolin dissolves easily in water, feels lighter on the skin, and is much easier to wash off, making it ideal for shampoos and light lotions.

