A potent postbiotic lysate that stimulates the skin’s endogenous production of ceramides by delivering bacterial enzymes. This filtrate excels at reinforcing the skin barrier, increasing hydration levels, and supporting a healthy microbiome through biotechnology.
- INCI Name:
- Streptococcus Thermophilus Ferment Filtrate
- Chemical/Scientific Name:
- Filtrate of the product obtained by the fermentation of Streptococcus thermophilus
- Common Aliases:
- S. Thermophilus Lysate, Probiotic Ferment Filtrate
| Category: | Active Substances, Moisturizers |
| Source Origin: | Biotechnology (Microbial Fermentation) |
| Comedogenic Rating: | 0 |
| Primary Industries: | Skincare, Dermatology, Microbiome Health |
| Solubility: | Water-soluble |
At a Glance: Properties & Effects
| Barrier Repair: | |
| Hydration/Moisture: | |
| Soothing/Calming: | |
| Irritation Risk: |
- Primary Benefits:
- Increases levels of Ceramide Np and other essential lipids in the stratum corneum.
- Supports the skin’s natural defense system against environmental pathogens.
- Reduces transepidermal water loss (TEWL) to maintain long-term hydration.
- Provides relief for sensitive, reactive, or compromised skin types.
- Potential Risks:
- Extremely low risk of irritation; generally suitable for all skin types.
- Bacterial lysates are non-living and do not pose an infection risk.
Biological Action & Cosmetic Profile
Dermatological efficacy of this ferment filtrate centers on its high concentration of the enzyme neutral sphingomyelinase. Research published in journals such as the *International Journal of Cosmetic Science* demonstrates that this specific enzyme triggers the conversion of sphingomyelin into ceramides within the skin’s upper layers. Unlike topical applications that merely sit on the surface, this biological trigger encourages the skin to synthesize its own structural lipids, resulting in a more resilient and self-sustaining moisture barrier.Microbiome modulation represents another critical function of this ingredient. As a postbiotic, the filtrate contains metabolites and cellular components that serve as a food source or signaling molecules for beneficial skin flora. By fostering a balanced microbial environment, the substance helps suppress the overgrowth of harmful bacteria like *Staphylococcus aureus*, which is often implicated in inflammatory conditions such as atopic dermatitis.Hydration capacity extends beyond simple occlusion. The fermentation process yields various Amino Acids and organic acids, including Lactic Acid, which contribute to the Natural Moisturizing Factor (NMF). These humectants draw moisture into the skin while the newly synthesized ceramides lock it in, providing a dual-action approach to dryness and dehydration.
Broader Applications & Origins
Streptococcus thermophilus is a lactic acid bacterium widely recognized for its use in the food industry, specifically in the production of yogurt and cheese. In a cosmetic context, the bacteria are cultivated in a controlled medium and then undergo lysis—a process that breaks the cell walls. The resulting liquid is filtered to remove live bacteria, leaving behind a nutrient-rich “broat” of enzymes, peptides, and polysaccharides that are shelf-stable and safe for topical use.
Routine Integration
- Synergies:
- Barrier Recovery: Works exceptionally well with Niacinamide to boost lipid production and Panthenol for accelerated wound healing.
- Intense Hydration: Combining it with Glycerin or Sodium Hyaluronate creates a comprehensive moisture-binding system.
- Lipid Replenishment: Pairs effectively with topical Cholesterol and Phytosphingosine to mimic the skin’s natural lipid ratio.
- Conflicts:
- No known biochemical conflicts; however, it is most effective in formulations with a pH close to that of the skin (approx. 4.5–5.5).
Clinical Consensus & Safety
Dermatological assessments from the Cosmetic Ingredient Review (CIR) and European regulatory bodies categorize this ferment filtrate as safe for use in leave-on and rinse-off cosmetic products. Clinical studies have specifically highlighted its utility in managing xerosis (pathological dryness) and improving skin comfort in patients with compromised barriers. Because it is a non-living filtrate, it does not require the intensive preservative loads sometimes associated with live probiotic technologies, making it a stable choice for sensitive skin formulations.
Is this a “live” probiotic?
No, it is a ferment filtrate, often categorized as a postbiotic. It contains the beneficial byproducts and enzymes of the bacteria, but the living organisms have been filtered out for safety and stability.
Can it help with acne?
While not a direct anti-acne agent, it helps balance the skin’s microbiome and strengthens the barrier, which can reduce the inflammation and sensitivity often associated with acne and harsh acne treatments.
How does it differ from Bifida Ferment Lysate?
While both are postbiotics, S. thermophilus is uniquely valued for its specific ability to stimulate ceramide production via sphingomyelinase, whereas Bifida lysates are more frequently used for DNA repair support and UV damage protection.